October 24, 2026

Omega-3 Basics: EPA, DHA and How to Read a Fish Oil Label

Nordic Naturals Ultimate Omega 2X softgels

Omega-3 fatty acids are among the most popular supplements in the US. But fish oil labels can be confusing. Here is what to look for.

EPA and DHA

The two omega-3s most often found in fish oil are EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid). When comparing products, look at the combined amount of EPA and DHA per serving, not just the total fish oil.

Check the serving size

A label might list a large amount of omega-3s, but the serving may be two or more softgels. Divide by the number of softgels to compare products fairly.

Triglyceride vs. ethyl ester

Omega-3s come in different chemical forms. Some brands, like Nordic Naturals and PRN De3, use the triglyceride or re-esterified triglyceride (rTG) form. Your label will usually say which form is used.

Other omega-3 sources

Some products use other marine sources, such as the green-lipped mussel oil in OmegaXL. If you have a fish or shellfish allergy, always read the allergen statement.

Freshness and taste

Lemon-flavored softgels can help with aftertaste. Store fish oil away from heat and light and use it before the expiration date.

Talk to your healthcare provider

If you take blood thinners, are pregnant or nursing, or have a medical condition, ask your doctor before taking omega-3 supplements.

Explore our Heart & Joint collection for name-brand omega-3s, all factory-sealed with free US shipping.

These statements have not been evaluated by the Food and Drug Administration. This content is for general information only and is not intended to diagnose, treat, cure or prevent any disease.